【洁尔阴洗液是哪个国家的品牌？】

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恩威洁尔阴洗液自1987年问世以来，其确切疗效和品牌深得广大患者、消费者和医务工作者的信赖，并于1991年成功进入香港、英联邦及马来西亚等国际市场，2002年进入美国药品市场。在国内，洁尔阴洗液得到国家卫生部认可，先后在1993年被批准为中药第三类新药［（93）Z－32号］，1997年被批准为中药保护品种［（97）卫药中保字085号］，1998年被批准为中药第五类新药［（98）Z－108号］，同年被上海市纳入公费医疗、劳保医疗报销范围，1999年又被四川省评为名牌产品。2002年被国家药监局转为国药准字Z10930008号药品。

药效学研究表明洁尔阴洗液有如下几方面的作用：

1、对致病微生物具有广谱杀灭作用。对常见致病菌，如：金黄色葡萄球菌、大肠杆菌、伤寒杆菌痢疾杆菌、和淋球菌等均有较强的抑菌作用；对常见皮肤癣病的致病菌如絮状表皮癣菌、许兰氏毛癣菌等有抑制和杀灭作用；对单纯疱疹Ⅱ型病毒具有较强的灭活作用，对沙眼衣原体和阴道滴虫有明显抑制及杀灭作用。

2、抗炎作用：经小鼠抗炎试验证明，洁尔阴洗液能明显抑制巴豆油所致的小鼠耳肿胀。

3、提高免疫功能：洁尔阴洗液具有较强机体细胞免疫的功能，能促进巨噬细胞的吞噬作用和白细胞的杀菌作用。

从对小鼠毒理试验来看，洁尔阴洗液对小鼠灌胃致死的用量远远超过人的用量说明本制剂安全性大；与家兔完整和损伤皮肤接触毒理实验未见有家兔全身及局部的毒性反应，皮肤和粘膜无刺激性和过敏反应。

从临床使用情况来看，洁尔阴洗液稀释后使用，未发现有任何副作用，未发现造血系统和肝肾功能损害，仅有个别患者局部有轻微的刺激反应，但可耐受，不需处理，不影响继续治疗。

洁尔阴洗液的适用范围除产品说明书中所列的疾病外，还广泛应用于以下疾病：

妇科病：慢性宫颈炎。

皮肤病：外耳湿疹、肛门湿疹、外阴湿疹、尿布皮炎、脂溢性皮炎、自体敏感性皮炎、隐翅虫皮炎、日光性皮炎、药疹、夏季皮炎、虫咬皮炎、荨麻疹、瘙痒症、扁平苔藓、肛门瘙痒、皮肤划痕症、丘疹性荨麻疹、痒疹、结节性痒疹、头癣、须癣、手足癣、甲癣、花斑癣、红癣、叠瓦癣、手足皲裂、酒渣鼻、痤疮、痱子、汗疱疹、冻疮、烧伤、多形红斑、疣、传染性软疣、白塞氏病、毛囊炎、丹毒、须疮、脓疱疮、斑秃、银屑病、粘膜白斑、神经性皮炎、玫瑰糠疹、臭汗症。

性病：淋病、梅毒、尖锐湿疣、非淋菌性尿道炎。

预防保健：产科术前术后消毒、外伤冲洗换药、日常保洁。

1992年在广州中医学院临床药理基地、广州中医学院附院、广东省中医院、成都市中医医院、成都中医学院附院、四川省人民医院对洁尔阴洗液治疗妇科、皮肤科疾病做临床床试验结果表明：洁尔阴洗液具有燥湿杀虫、祛风止痒的功效，临床应用安全，极少见不良反应，在妊娠期使用，未见对胎儿致畸等副作用。说明洁尔阴洗液是一种对皮肤、外阴、阴道炎的多种致病病原体均有杀灭或抑制作用的外用中药。

英文翻译：Since its inception in 1987, Enwei Jieeryin lotion has won the trust of patients, consumers and medical workers for its exact efficacy and brand. It has successfully entered the international markets such as Hong Kong, the Commonwealth and Malaysia in 1991, and the United States in 2002. In China, Jieeryin lotion has been approved by the Ministry of health of the people's Republic of China. In 1993, it was approved as the third class new drug of traditional Chinese medicine [(93) Z-32], in 1997, it was approved as the protection variety of traditional Chinese medicine [(97) Wei Yao Zhong Bao Zi 085], in 1998, it was approved as the fifth class new drug of traditional Chinese medicine [(98) z-108], and in the same year, it was included in the reimbursement scope of public medical treatment and labor insurance medical treatment in Shanghai It is also rated as a famous brand product by Sichuan Province. In 2002, it was transferred to gyzz z10930008 by the State Food and drug administration. Pharmacodynamic study shows that Jieeryin lotion has the following functions: 1. It has broad-spectrum killing effect on pathogenic microorganisms. It has strong bacteriostatic effect on common pathogenic bacteria, such as Staphylococcus aureus, Escherichia coli, Shigella typhi, gonococcus, etc.; it has inhibition and killing effect on common dermatophytosis, such as flocculent epidermis, Trichophyton Xu LAN, etc.; it has strong inactivation effect on herpes simplex type II virus, and has obvious inhibition on Chlamydia trachomatis and Trichomonas vaginalis And killing effect. 2. Anti inflammatory effect: the anti-inflammatory test of mice showed that Jieeryin lotion can obviously inhibit the ear swelling of mice caused by croton oil. 3. Improve the immune function: Jieeryin lotion has a strong cell immune function, which can promote the phagocytosis of macrophages and the bactericidal effect of leukocytes. According to the toxicological test on mice, the dosage of Jieeryin lotion for lethal mice by gavage is far more than that of human, which indicates that the preparation is safe; no systemic and local toxic reaction is found in the toxicological test of contact with intact and damaged skin of rabbits, and no irritative and allergic reaction is found in skin and mucosa. From the perspective of clinical use, no side effects were found after the use of Jieeryin lotion diluted, no damage to the hematopoietic system and liver and kidney function was found, and only a few patients had slight local stimulation response, but it was tolerable, without treatment, and did not affect the continued treatment. In addition to the diseases listed in the product manual, Jieeryin lotion is also widely used in the following diseases: gynecological diseases: chronic cervicitis. Skin diseases: eczema of the outer ear, eczema of the anus, eczema of the vulva, diaper dermatitis, seborrheic dermatitis, auto sensitive dermatitis, dermatitis of Paederus, dermatitis of the sun, drug rash, dermatitis of the summer, dermatitis of the insect bite, urticaria, pruritus, lichen planus, pruritus of the anus, skin scratch, urticaria papulosa, pruritus, pruritus nodosa, pruritus, tinea capitis, tinea palpis, tinea manus and pedis, tinea, onychomycosis Tinea versicolor, tinea rubrum, tinea imbricata, rhagadosis of hands and feet, rosacea, acne, prickly heat, herpes perspirata, frostbite, burn, erythema multiforme, verruca, infectious soft wart, Behcet's disease, folliculitis, erysipelas, fester, pustular, alopecia areata, psoriasis, leukoplakia mucosa, neurodermatitis, pityriasis rosea, and dyshidrosis. Venereal disease: gonorrhea, syphilis, condyloma acuminatum, nongonococcal urethritis. Prevention and health care: disinfection before and after obstetric operation, washing and dressing change for trauma, daily cleaning. In 1992, in the clinical pharmacology base of Guangzhou University of traditional Chinese medicine, Affiliated Hospital of Guangzhou University of traditional Chinese medicine, Guangdong Hospital of traditional Chinese medicine, Chengdu Hospital of traditional Chinese medicine, Affiliated Hospital of Chengdu University of traditional Chinese medicine and Sichuan people ' Should be used in pregnancy, no side effects such as fetal teratogenesis. It shows that Jieeryin lotion is a kind of external Chinese medicine which can kill or inhibit many pathogenic pathogens of skin, vulva and vaginitis.

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