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苏州瑞博生物技术有限公司（以下简称：瑞博），是开发基于RNA干扰（RNAi）技术的核酸药物的创新型研发企业，是中国小核酸技术和小核酸制药产业的主要开拓者。瑞博经过七年多的发展，已经形成了从临床前到临床的丰富的产品链，极大的推动了中国以及亚洲地区的核酸类药物研究。
瑞博自成立以来，以科学引导技术，以技术引导产品，在小核酸（siRNA）药物研发、小核酸的规模化生产、原料药质量研究和GMP生产线建设和GMP管理方面均取得了长足的发展。瑞博自主研发的小核酸液相技术已进入到中试规模工艺优化阶段，这一成就使得瑞博一举跻身于世界核酸产品制备技术的前列；瑞博拥有规模化生产小核酸的GMP生产线，该设施为瑞博的小核酸药物品种研制和技术创新提供了强有力的支持，同时也为国内外多家公司的核酸药物开发提供了支撑；瑞博在药物靶点发现、靶点活性筛选、给药途径、药效药理、安全性评价、临床研究等诸方面逐步建立起相对完善的小核酸创新药物研究体系。其中尤其对各种类型的核酸递药载体进行了系统的开发研究和功效评价，并围绕其中的较优载体形成了药物品种开发产品链。
英文翻译：Suzhou Ruibo Biotechnology Co., Ltd. (hereinafter referred to as "Ruibo") is an innovative R & D enterprise to develop nucleic acid drugs based on RNA interference (RNAi) technology, and a major pioneer in China's small nucleic acid technology and small nucleic acid pharmaceutical industry. After more than seven years of development, Rambo has formed a rich product chain from preclinical to clinical, which has greatly promoted the research of nucleic acid drugs in China and Asia. Since its establishment, Rambo has made great progress in the research and development of small nucleic acid (siRNA) drugs, large-scale production of small nucleic acid, quality research of APIs, construction of GMP production line and GMP management with science guiding technology and technology guiding products. The small nucleic acid liquid phase technology independently developed by Rabo has entered the stage of pilot scale process optimization, which makes Rabo rank in the forefront of nucleic acid product preparation technology in the world; Rabo has a GMP production line for large-scale production of small nucleic acid, which provides strong support for the research and development of small nucleic acid drug varieties and technical innovation of Rabo, as well as for many companies at home and abroad We have established a relatively perfect research system of small nucleic acid innovative drugs in the aspects of drug target discovery, target activity screening, drug delivery route, pharmacodynamics, safety evaluation, clinical research and so on. In particular, various types of nucleic acid delivery carriers are systematically researched and evaluated, and a product chain of drug variety development is formed around the better carriers.
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